Bioenergy RIBOSE & Caffeine
Solution for
 Decreased Fatigue/Increased Alertness/Elevated Mood  Higher Sport Performance  Cognitive/Mental Health  Cardiovascular Health D-Ribose, or simply ribose, is an aldopentose (5-carbon monosaccharide with an aldehyde functional group)
which is used by all cells of the body. Ribose is an essential structural component of energy currency Adenosine triphosphate (ATP) as well as several other compounds that are critical to metabolism. Ribose also comprises the backbone of RNA and is related to DNA. Forming ribose in heart and muscle is a slow process which, in turn, delays energy recovery when energy pools have been depleted by disease or exercise. Ribose restores and maintains depleted energy reserves. Ribose is often marketed as a supplement for boosting energy and reducing fatigue in: post exercise (muscle cramping and soreness), fibromyalgia Ribose also increases cardiac efficiency, power output and tolerance to stress. Bioenergy RIBOSE is GRAS (absorption of 95% with peak blood levels found within 30-45 min). The recommended daily dose depends on the product benefit (e.g., up to 1.5g for energy, up to 7 g for physical performance and up to 10 g for cardiovascular and general health). Caffeine is a bitter, white crystalline xanthine alkaloid which is found in many plants such as coffee, tea, and to
a lesser extent chocolate derived from cocoa beans. Less commonly used sources of caffeine include the yerba
maté and guarana plants. Caffeine content in coffee is in the range of 40 to 100 mg/cup.
Soft drinks typically contain about 10 to 50 mg/240 ml and energy drinks such as Red
Bull® has 80 mg/per 250 ml. The disparity in experience and effects between the various
natural caffeine sources could be because plant sources of caffeine also contain widely
varying mixtures of other xanthine alkaloids theobromine and theophylline, and
polyphenols that can form insoluble complexes with caffeine. Caffeine from coffee or
other beverages is absorbed by the stomach and small intestine within 45 minutes of ingestion. In humans,
caffeine is a central nervous system stimulant, having the effect of temporarily warding off drowsiness, decreased
fatigue, increased awareness/alertness/attentiveness, and elevating one's mood. With these effects, caffeine is an
ergogenic (increasing a person's capability for mental or physical labor). Caffeine's principal mode of action is as
a nonselective antagonist of adenosine receptors in the brain. Caffeine is metabolized in the liver into three
primary dimethylxanthine metabolites: paraxanthine (84%), theobromine (12%), and theophylline (4%) which
also contribute to caffeine's effects. In healthy adults, caffeine's half-life is about 5 hours. Caffeine is the most
widely consumed legal and unregulated psychoactive substance but overdose (>300 mg/day) must be avoided.
Advantages of combining Bioenergy RIBOSE and Caffeine
There seems to be a logical synergy for combining ribose and reasonable doses of caffeine. Caffeine has been
proven to decreased fatigue, increased alertness and elevated mood while ribose helps make the energy and higher
sport performance. As a result, combination of caffeine and ribose should show combination of these effects and
possibly improved cognitive and mental health.
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