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Journal of Cardiac Failure Vol. 14 No. 6 2008 Pioglitazone and Heart Failure: Results From a Controlled Study in Patients With Type 2 Diabetes Mellitus and Systolic Dysfunction THOMAS D. GILES, ALAN B. MILLER, MD,URI ELKAYAM, MONDIRA BHATTACHARYA, MD,AND ALFONSO PEREZ, New Orleans, Louisiana; Jacksonville, Florida; Los Angeles, California; Deerfield, Illinois Background: Thiazolidinediones are associated with fluid retention, often interpreted as worsening car-diac function, limiting their use in patients with heart failure (HF). We compared the effects of pioglita-zone and glyburide on cardiac function in patients with type 2 diabetes, systolic dysfunction, and NewYork Heart Association (NYHA) functional Class II/III HF.Methods and Results: Participants received pioglitazone or glyburide (6insulin) for 6 months in thisdouble-blind, randomized, multicenter study. The primary end point was time to HF, a composite ofcardiovascular mortality and hospitalization or emergency room (ER) visit for HF. Secondary endpointsincluded echocardiographic and functional classification assessments. An earlier time to onset and higherincidence of the primary endpoint was noted with pioglitazone (13%) versus glyburide (8%) (P 5 .024).Hospitalization or ER visit occurred in 30 pioglitazone and 15 glyburide participants, 19 and 12 of whom,respectively, continued treatment. Cardiac mortality (5 versus 6 participants, respectively) and cardiacfunction, as measured by change in ventricular mass index (P 5 .959), ejection fraction (P 5 .413), orfractional shortening (P 5 .280), were similar between treatments.Conclusions: Pioglitazone was associated with a higher incidence of hospitalization for HF without anincrease in cardiovascular mortality or worsening cardiac function (by echocardiography). (J CardiacFail 2008;14:445e452)Key Words: Cardiovascular disease, thiazolidinediones, left ventricular dysfunction.

Première Edition des Rencontres Africaines pour le Développement de la Petite Enfance au niveau Actes de la Conférence Cotonou-Bénin, 27 novembre 2012 Introduction La Première Edition des Rencontres Africaines pour le Développement de la Petite Enfance a été organisée au Bénin du 26 au 30 novembre 2012 autour du Thème « Développement Communautaire et Petite Enfance » Les rencontres ont été le fruit d'un partenariat dynamique entre le Gouvernement du Bénin, le Groupe de Travail de l'ADEA pour le développement de la petite enfance (GTDPE), l'Organisation des Nations Unies pour l'Education, la science et la culture (UNESCO) et le Réseau pour l'Education Pour Tous en Afrique (REPTA) en partenariat avec le Groupement des Retraités pour l'Education sans Frontières (GREF) et les Centres d'Entrainement aux Méthodes Actives (CEMEA). Elles ont été cofinancées par l'AFD, l'ADEA, l'UNESCO et le REPTA. Elles sont le couronnement de six mois de préparatifs menés avec les cellules nationales du REPTA, les équipes pays GREF et CEMEA, les réseaux nationaux DPE membres du GTDPE de l'ADEA dans les pays de les pays francophones de l'Afrique de l'Ouest et du Centre. Les rencontres avaient pour thème « Comment valoriser la contribution des organisations communautaires de base ». Ce thème a été abordé au travers de quatre sous thèmes que sont :

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in the treatment ofendometriosis Nicolo Bizzarri, Valentino Remorgida, Umberto Leone Roberti Maggiore, Carolina Scala, Emanuela Tafi, Valentina Ghirardi, Stefano Salvatore,Massimo Candiani, Pier Luigi Venturini & Simone Ferrero† †University of Genoa, IRCCS San Martino Hospital and National Institute for Cancer Research, Pharmacokinetic of DNG Department of Obstetrics and Gynaecology, Genoa, Italy

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JOURNAL OF TEACHING AND LEARNING, 2012, VOL. 8, NO. 2 Exemplary Teaching Practices Across Educational Contexts (P-20+): Unifying Principles and an Ecological Model for Teaching for All to Learn Judith Ableser Ph.D. Oakland University Abstract This paper highlights that teaching for all to learn is a central theme of exemplary practice across all educational contexts from preschool through graduate school (P-20+). Ten unifying principles will be presented based on this theme. Although these principles are consistent across P-20+ settings, the ways in which these practices are implemented will differ, depending on the context. An ecological model for teaching for all to learn will be developed, presenting a conceptual schema of the components and factors involved in exemplary teaching across all contexts from preschool, special education, elementary, secondary, through all levels of higher education.


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Occurrence of Estrogenic Endocrine Disruptors in Groundwater Wisconsin State Laboratory of Hygiene Investigators: William Sonzogni PhD, Director Jocelyn Hemming, PhD, Assistant Scientist Miel Barman, Environmental Toxicologist Steve Geis, Chemist Supervisor July 1, 2004-June 30, 2006 This project was supported, in part, by General Purpose Revenue funds of the State of Wisconsin

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These e-Updates are a regular weekly item from K-State Extension Agronomy and SteveWatson, Agronomy e-Update Editor. All of the Research and Extension faculty in Agronomywill be involved as sources from time to time. If you have any questions or suggestions fortopics you'd like to have us address in this weekly update, contact Steve Watson,785-532-7105, Jim Shroyer, Crop Production Specialist, or Curtis Thompson, Extension Agronomy State Leader and WeedManagement Specialist 785-532-3444

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Int. J. Biomedical Engineering and Technology, Vol. 1, No. 4, 2008 Dynamic generation of a Health Topics Overview from consumer health information documents Trudi Miller* and Gondy Leroy School of Information Systems and Technology, Claremont Graduate University, 130 E. Ninth Street, Claremont, CA 91711, USA E-mail: E-mail:


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