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Daubert:The Most Influential Supreme Court Ruling You've Never Heard Of A Publication of the Project on Scientific Knowledge andPublic Policy, coordinated by the Tellus Institute Daubert:The Most Influential Supreme Court Ruling You've Never Heard Of A Publication of the Project on Scientific Knowledge andPublic Policy, coordinated by the Tellus Institute

Microsoft word - sleep disorders.docx

Sleep Disorders 1. Primary hypersomnia 2. Primary insomnia 3. Narcolepsy 4. Breathing-related sleep disorder 5. Circadian rhythm sleep disorder 6. Nightmare disorder 7. Sleep terror disorder 8. Sleepwalking disorder 1. Primary hypersomnia The defining feature of primary hypersomnia (also cal ed idiopathic hypersomnia) is excessive sleepiness that has lasted for at least one month as manifested by prolonged sleep episodes at night or in the day. Excessive sleepiness during the day may result in long naps that fail to al eviate sleepiness, and other associated symptoms include prolonged sleep at night (which can last for 12 hours or more) as wel as sleep drunkenness. Sleep drunkenness describes a drawn out transition from sleep to waking, during which the person is apparently in a state of inebriation, exhibiting partial alertness, disorientation, drowsiness, poor coordination, and even agitated or violent behaviour. Because the person does not feel wel rested even after taking naps, they constantly struggle to stave off feelings of sleepiness. Hypnagogic hal ucinations and sleep paralysis are rare, but may be found among those with primary hypersomnia. The onset of this disorder typical y occurs before the age of 30 and continues on a chronic course unless treated.

Promega notes 100: novel biosensors to monitor cellular events in live cells

LIVE-CELL BIOSENSOR Novel Biosensors to Monitor Cellular Events in Live Cells Review of Fan, F. et al. (2008) Novel genetically encoded biosensors using firefly luciferase. ACS Chem. Biol. 3, 346–51. Neal Cosby, Promega Corporation entists targeted the hinge region of the luciferase mol- Drug discovery and life science researchers desire to


patterns—electric blue in the westernCaribbean, lemon yellow in the Northern Why Gobies Are Like Hobbits Bahamas, and stark white in the eastern Stephen R. Palumbi and Robert R. Warner Caribbean—might be local signals to preda-tors that these gobies are the valet service As Bilbo Baggins famously warned, trav- genetic breaks between island groups that rather than the entrée. If this is true, then the

Microsoft word - pcd nb.doc

REPOBLIKAN'I MADAGASIKARA Tanindrazana – Fahafahana – Fandrosoana COMMUNE URBAINE NOSY BE DISTRICT NOSY BE PROVINCE ANTSIRANANA I – Monographie b. De 1840 à 1896 c. De 1896 à 1960 d. De 1960 à nos jours 2. Situation géographique et délimitation administrative a. Situation géographique b. Organisation administrative 3. Les acteurs de développement

Dementi till tidningen

Dementi till Helsingborgs Dagblad – begäran om omgående genmäle Anders Sultan kräver att tidningen går ut med en dementi samt att genmäle bereds. För det första så har Anders Sultan i Helsingborgs Dagblad utsatts för grovt förtal, då han i HD:s artikelserie utmålas som klandervärd och brottslig. För det andra så har Anders Sultan och Michael Zazzio inte fått avge sin sida av saken till tidningen. Anders Sultan nekades att få frågorna skriftligen inför intervju, samt så har journalisten ej ringt tillbaka till Michael Zazzio, talesman och styrelseordförande för Ion Silver då denne ville samtala kring den förestående artikeln. För det tredje så baseras HD:s tidningsartikel på uppgifter från en sluten facebooksida vilket strider mot de pressetiska reglerna. Anders Sultan har agerat som privatperson i ett slutet forum – och kan i detta forum enligt Europakonventionen för mänskliga rättigheter gällande yttrandefriheten – yttra precis vad han vill. Företaget Ion Silver är en egen juridisk person och kan i detta fall inte sammanblandas med privatpersonen Anders Sultan. För det fjärde så har Anders Sultan vetenskapliga belägg för sina påståenden. Till och med Anders Tegnell på Folkhälsomyndigheten sade för en och en halv vecka sedan, i ett telefonsamtal med Michael Zazzio: "Att det är känt att kolloidalt silver fungerar på de flesta virus" (lyssna på bifogad ljudfil: anders_tegnell.wav). Inte nog med att expertisen i Sverige vet detta. Det finns även ett hundratal MEDLINE-indexerade studier om kolloidalt silver och dess effekt på olika skadliga mikroorganismer såsom virus, bakterier, svamp samt encelliga organismer. Det finns även över 500 sidor användarberättelser som erfarenhetsmässigt även vittnar om positiva bieffekter i form av förbättrat hälsotillstånd när konsumenter har använt den silverhaltiga vattenreningsprodukten. Kolloidalt Silver, Ionosil säljs och marknadsförs som vattenreningsprodukt och får som sådan enligt kemikalieinspektionen ettiketteras som verksam mot mikroorganismer genom sitt innehåll av silver. För det femte så är kolloidalt silver ofarligt. Världshälsoorganisationen, WHO:s säkerhetsdata för rent silver, visar att man kan konsumera upp till 10 gram rent silver under en livstid om 70 år utan att överskrida myndighetens ‖nolleffektdos‖ – NOAEL, No Observed Adverse Effect Level – det vill säga den högsta dos som man kan exponeras för utan att riskera några som helst negativa hälsoeffekter. Det motsvarar ca 390 mikrogram per person och dag. Detta är enligt WHO en garanterat oskadlig dos för människan.


SAFETY PROFILE OF RUPATADINE IN THE TREATMENT OF CHRONIC URTICARIA Giménez-Arnau A1, Malbran A2, Poop G3, Benea V4, Medina I5, Garcia O6, Donado E6 1Hospital del Mar, Dermatology Department, IMAS. Barcelona, Spain. 2Unidad de Alergia, Asma o Inmunología-COM. Buenos Aires, Argentina. 3Dermatological Clinical Practica. Augsburg, Germany. 4Clinical Hospital Prof Scarlat Longhin. Bucharest, Romania.

Powerpoint template 16x9

Implementation of QbD for Existing Products An Example from GSK Australia Jonathan Parks B.Sc (Hons) from Monash University in 1990 Started at Glaxo (as it was called then) in 1991 as a Development Chemist in Pharmaceutical Development Worked on the development of Blow-Fill-Seal (BFS) products for nebulisation and Dry Powder Inhalation (DPI) products

Microsoft word - web supplement sans line numbers reformat citations.doc

Supplementary Appendix This appendix has been provided by the authors to give readers additional information about their work. Supplement to: Turner EH, Matthews AM, Linardatos E, et al. Selective publication of antidepressant trials and its influence on apparent efficacy. N Engl J Med 2008;358:252-60. SELECTIVE PUBLICATION OF ANTIDEPRESSANT TRIALS AND ITS INFLUENCE ON APPARENT EFFICACY


en el contexto de la etología y la antropología* Aggressiveness in the ethology and anthropology A agressão no contexto da etologia e a antropologia* Juan Alejandro Brando** • Argentina Recibido el 12 de septiembre de 2012, aceptado el 24 de enero 2013 ** Este trabajo es parte de la investigación conducente al doctorado en filosofía por la Universidad Nacional de Lanús, la cual fue parcialmente financiada por una beca de postgrado tipo II del Consejo

Microsoft word - chapter_4_formatted_rt_tw_9dec2010.doc

Intellectual Property and Human Development Trends and scenarios in the legal protection of traditional knowledge Charles McManis and Yolanda Terán1 Introduction This chapter discusses the currently much debated issue of traditional knowledge (TK) protection. Opinions differ widely, not only as to how TK should be protected, but even as to whether TK should be protected at all. It is commonly accepted that intellectual property rights (IPRs) in their current form are ill-suited for this category of knowledge. But does it follow that TK should be placed or left in the public domain for anybody to use as they wish? For many indigenous peoples, traditional communities and developing country governments, this seems neither fair nor reasonable. In response, they have insisted that this issue be discussed at the highest level in such forums as the World Intellectual Property Organization (WIPO), the World Trade Organization (WTO) and the Convention on Biological Diversity (CBD) Conference of the Parties (COP), and also be addressed at the national and regional levels. Proposals have included reforms to current IP regimes in order to prevent misappropriation of TK and the development of sui generis systems that vest rights in TK holders and TK-producing communities. However, considerable conceptual and political difficulties remain, and these remaining difficulties make it hard to predict the future of TK, as a legal and diplomatic issue.

Postnote template

January 2010 Number 352 COUNTERFEIT MEDICINES Counterfeiting of medicines is increasing, is often linked to other criminal activities and poses risks to public health. It exposes people to medicines of unverified quality, safety and efficacy. This POSTnote considers the extent of the global counterfeit medicine trade, its impact in the UK and the technologies and policy options available to combat it. It also examines the risks and benefits of online pharmacy, one of the main ways in which counterfeits are distributed.


Proceeding of 6th ICGRC 2015 6-Gingerol from Zingiberaceae as a Result of Reverse Docking for Prostate's Cancer Potential Drug Candidate Haqqi Anajili Setyanto1, Arindra Trisna Widiansyah1, Zainul Mustofa1 1 Postgraduate of Educational Biology, State University of Malang, Malang, Indonesia Prostate cancer is a cancer that attacks the prostate gland causing the death rate which is high enough. One of the causes ofprostate cancer is the androgen receptor (AR) in the gland cells that initiates the formation of excess cell proliferation, thuscausing prostate cancer. AR inhibitor that is known is antiandrogen (biculatamide and enzalutamide). This study aimed to test the6-gingerol compound of ginger as an AR inhibitor drug candidate for prostate cancer using silico methode. The 3D structure ofthe 6-gingerol compound was taken from PubChem, the prediction of targeted protein used SwissTargetPrediction andPharmapper, analysis and docking 6-gingerol and antiandrogens with AR using Pyrx software, visualization compounds andprotein interactions using PyMOLsoftware. Visualization results shows that the interaction of 6-gingerol, biculatamide, andenzalutamide with AR have the same site. This proves that the 6-gingerol is potential as anAR inhibitor candidate.

Microsoft word - guidanofollonica1993.docx

VITTORIO F. GUIDANO LA PSICOTERAPIA COGNITIVISTA POST-RAZIONALISTA NEI SERVIZI PUBBLICI EBOOK Psicoterapia e Scienza Roma 2012 VITTORIO F. GUIDANO LA PSICOTERAPIA COGNITIVISTA POST-RAZIONALISTA NEI SERVIZI PUBBLICI "Sbobinatura" di un seminario sul 'applicazione del model o post-razionalista nei Servizi Pubblici che Vittorio Guidano tenne nel 1993. All'esposizione teorica segue la supervisione di un caso di psicosi ove si mostra chiaramente come l'utilizzo del model o post-razionalista permetta un particolare inquadramento del caso clinico e del processo terapeutico, discusso in maniera molto ricca nel 'ultima parte dell'articolo.

Organon mexicana, s

INFORMACIÓN PARA PRESCRIBIR AMPLIA Acetato de Nomegestrol / Estradiol 1. NOMBRE COMERCIAL: ZOELY® 2. NOMBRE GENÉRICO: Acetato de Nomegestrol / Estradiol 3. FORMA FARMACÉUTICA Y FORMULACIÓN: Tabletas Cada tableta contiene: Acetato de nomegestrol Excipientes c.b.p. Las tabletas amaril as no contienen sustancias activas placebo.


Volume 5 Issue 2 Apr-Jun 2015 Renal and Hepatic Antioxidant Status of Hyperglycemic Rats Treated with Single and Combinatorial Herbal Formulations.Okey Alphosus Ojiako1, Paul Chidoka Chikezie2, Agomuo Chizaramoku Ogbuji31Department of Biochemistry, Federal University of Technology, Owerri, Nigeria 2Department of Biochemistry, Imo State University, Owerri, Nigeria3Department of Food Science and Technology, Abia State Polytechnic, Aba, Nigeria


Organometallics 2008, 27, 1384–1392 Theoretical Studies of the sp2 versus sp3 C-H Bond Activation Chemistry of 2-Picoline by (C5Me5)2An(CH3)2 Complexes (An ) Th, U) Ping Yang,* Ingolf Warnke,† Richard L. Martin, and P. Jeffrey Hay* Los Alamos National Laboratory, Los Alamos, New Mexico 87545 ReceiVed September 18, 2007


Glimpses of the Workshop Today commercialization of agriculture is an inevitable reality throughout the whole world. There are a number of factors affecting the commercialization process in agriculture. Some of them could be named as rapid growth of economies in the developing and developed countries, introducing of new technologies, market expansion, market liberalization, urbanization, rapid increase of demand for food,